Friday, March 17, 2006
[evomech] At Berkeley: Intelligently Designed Molecular Evolution (Research
BERKELEY, CA - Evolutionary paths to new therapeutic drugs, as well as a wide assortment of other enzyme products, have been created through, of all things, intelligent design. A team of researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California at Berkeley have developed a technique in which the evolution of an important class of proteins is steered towards a desired outcome.
"We've taken enzymes that are promiscuous, meaning they have the capacity to evolve along many different functional lines, and trained them to become specialists," said chemical engineer Jay Keasling, who led this study.
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--Model of an Internal Evolutionary Mechanism:
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